Top 5 Liver Health Supplements of 2019

Updated 3/20/2019

An updated guide on what to look for in a quality liver support and our top 5 picks for 2019

The Body's Super Organ

The liver is located on the right side of the belly and sits just below your lungs. It's a vital organ protected by the rib cage... And for good reason! The liver is a superpower in the body. The liver is the largest and heaviest organ and is involved in over 500 roles in the human body. An even greater "superpower" is that the liver is the only organ that can regenerate. You can see why it's so close to the heart and lungs - it's a extremely vital part of the body.

    As you can see, an impaired liver could have a very negative impact on your health and well-being! On the flip-side, you can enjoy many benefits by improving the health of your liver. Potential benefits include (just to name a few!):

    • Healthy weight management
    • Increased energy and motivation
    • Improved mood and emotional well-being
    • Better sleep quality
    • Faster recovery from exercise
    • And much more!

      With all these amazing health benefits in mind, how do you choose a supplement to improve your liver health? Continue reading to find out!

      Choosing a Liver Health Supplement

      Key elements you should be looking for in a Liver Health Supplement

      1. Clinically Studied Ingredients 

      The most important factor in choosing a liver health supplement is the ingredients. While there are many ingredients that companies claim to be beneficial to liver support, there are only a few that have the research backing it up.

      The top 3 ingredients that have the most positive effect on liver health and have clinical studies to back it up are:

      • Tauroursodeoxycholic acid (TUDCA) - Multiple clinical studies have shown that TUDCA improves markers of liver health. It has been shown to be comparable or better than a similar prescription strength molecule called UDCA. This is a relatively new and novel ingredient that not many companies are using due to the high cost of such an effective molecule. 

      • Silybum marianum (Milk Thistle) - Lab studies suggest that silymarin helps regenerate liver tissue, bring down inflammation, and protect liver cells from damage by acting as an antioxidant. A 2017 study found that silymarin improved liver enzymes values in people with liver disease.

      • N-acetyl cysteine (NAC) -  Studies have shown that NAC supplementation is able to increase glutathione concentrations in the body, which protects the liver from free radical damage.  

        2. Efficaciously Dosed Ingredients 

        Now that you know which ingredients are the most effective for liver health, we need to make sure that these ingredients are in efficacious doses. An efficacious dose is a concentration or amount of an ingredient that is large enough to cause an intended effect.

        Different ingredients and compounds will require different efficacious doses. For the 3 ingredients mentioned above, the doses supported by research are:

        • Tauroursodeoxycholic acid (TUDCA)  300 - 600mg per day 
        • Silybum marianum (Milk Thistle) : 100-600mg per day
        • N-acetyl cysteine (NAC) :  200-800mg per day

          3. High Quality Ingredients

          We also need to factor in the quality of ingredients. The quality of the ingredient is just as important as the ingredient itself because low quality supplements do not produce results! Look for liver supplements that promote high quality ingredients. Some companies may also be able to provide independent testing of the quality of the ingredients. 

          High quality ingredients lead to more effective liver support and protection. 

            4. Inspected and Certified Manufacturer

            Next, you should look for companies with NSF or cGMP certifications. NSF is a product testing, inspection and certification organization that test dietary supplements for containments. The cGMP certification verifies that a supplement is made in a facility that follows strict regulatory guidelines. This assures proper monitoring and control of manufacturing facilities. A manufacturer should also be registered with United States FDA so that they compile with federal guidelines.

            Liver support supplements made in these facilities have higher standards of quality and consistency and should be a factor when deciding on a liver supplement. 

              5. Prioritized Customer Service

              Finally, when choosing a liver health supplement, you should look for companies that fully stand behind their product. Companies that offer 100% money back guarantees are more likely to believe in their product. There is less risk from buying from them because you can always return the product if it's not working for you. 

              You should also choose companies whose customer support is easily reachable to answer questions and concerns.  Companies who prioritize their customer service and satisfaction are usually the ones selling the best products!

                Our Top Liver Support Supplements for 2019

                A compiled list of our top 5 supplements that will help improve Liver Health.

                How did we rate these liver support supplements? Scroll up to read through our Tips for Choosing a Liver Health Supplement

                Scorecard

                Ingredients

                90%

                Effectiveness

                97%

                Value

                95%

                Customer Reviews

                93%

                Customer Support

                92%

                Score Summary

                We picked Liver IV as our top liver health supplement because it had innovative ingredients that delivered effective results. Liver IV is one of the few liver supplements we found that had a clinically studied dose of 500mg TUDCA per serving. Many companies did not have any TUDCA. 

                We like that Liver IV is made in a FDA registered and cGMP certified facility. Liver IV also had many positive customer reviews. The customer support was also very responsive and offered a full money back guarantee return for any reason. The price point was higher than some of the other liver supplements we reviewed, but with over 30g of TUDCA per bottle, we felt that it was very well worth it. Besides, you can't put a price tag on your health. Liver IV is our 2019 Top Pick for best liver health supplement. 

                Scorecard

                Ingredients

                80%

                Effectiveness

                88%

                Value

                82%

                Customer Reviews

                95%

                Customer Support

                85%

                Score Summary

                Nutricost TUDCA has 250mg TUDCA per serving, with 60 servings per bottle. We dinged some points because it did not have any other liver support ingredients and you have to take 2 servings to get an effective dose of TUDCA. 

                Nutricost supplements are made in a FDA registered and cGMP certified facility. This supplement also had positive customer reviews. However they only offer a money back guarantee on one used bottle and did not have any live customer support chat to answer lingering questions. 

                Overall we deemed TUDCA by Nutricost a good base level liver support product at an affordable price.

                Scorecard

                Ingredients

                80%

                Effectiveness

                82%

                Value

                79%

                Customer Reviews

                82%

                Customer Support

                75%

                Score Summary

                GSS Clear has 250mg TUDCA and 250mg NAC per serving. These are two ingredients we like to see in a liver supplement. But we had to deduct points from ingredients and effectiveness because we were not able to determine if this liver support supplement was manufactured in a certified and regulated facility. 

                This supplement had mostly positive customer reviews, but some customers indicated that there were no instructions on how to take it. There is no return policy for GSS Clear and support is by phone and email only.

                Overall Clear by GSS is a respectable liver supplement is you trust the brand and are comfortable with their customer support.

                Scorecard

                Ingredients

                71%

                Effectiveness

                65%

                Value

                70%

                Customer Reviews

                94%

                Customer Support

                75%

                Score Summary

                5% Nutrition Liver & Organ Defender has 1000mg NAC and 600mg Milk Thistle per serving for liver support. There is no TUDCA in this product. Each serving is also a whopping 9 capsules, so be prepared to ingest a lot of pills if you go for this supplement!

                We had to deduct points from ingredients and effectiveness because this supplement was not a liver health focused product. It tries to be a multi-organ support supplement but is just average in all aspects. We prefer specialized supplements that cater specifically to liver health.  We were also not able to determine if this liver support supplement was manufactured in a certified and regulated facility. 

                This supplement has mostly positive customer reviews. There is no guaranteed return policy but phone, email and live chat support was available for us.

                Overall Liver & Organ Defender by 5% Nutrition is a decent supplement for a basic whole body health aid, but it is lacking as a liver health supplement.

                Scorecard

                Ingredients

                55%

                Effectiveness

                55%

                Value

                70%

                Customer Reviews

                95%

                Customer Support

                75%

                Score Summary

                Arazo Nutrition Liver Cleanse claims to have 22 herbs to support liver health. However more than half of the ingredients were hidden behind a proprietary blend - meaning we do not know the exact doses of over half the ingredients. Many of the ingredients also did not have sufficient research backing it up, so we had to deduce points from effectiveness.  

                An effective liver supplement that is going to deliver results requires research backed ingredients. We did not find the key ingredients necessary for advanced liver support in this supplement.

                Liver Cleanse by Arazo Nutrition may be a good beginner product but would not be suited for those looking for the next level of liver support.